VaNae Hamilton is a technical advisor in the Intellectual Property Practice Group. She is a biotechnology and life sciences patent scientist with more than a decade of experience in molecular biology, immunology, biochemistry, and microbiology research. As a molecular biologist, VaNae primarily investigated protein trafficking in Trypanosoma brucei.
Upon completion of her doctoral studies at Meharry Medical College in Biomedical Sciences with an emphasis in Microbiology and Immunology, VaNae transitioned from bench research to patent prosecution. She is a graduate of the Master of Science in Patent Law program at the University of Notre Dame.
VaNae has experience in building patent portfolios protecting biologic, pharmaceutical, and diagnostic technologies; examples include: gene therapy, CAR-T cell therapies, antibody and protein therapeutics, CRISPR-Cas9 related technologies, diagnostic tests based on genomic signatures, genetically modified microbes for detection of analyte in a sample, methods of folding immunoproteins in vitro, methods of labeling and detecting macromolecules in an intact cell system, and combination therapies. She has also conducted extensive freedom-to-operate studies, diligenced potential acquisition targets, and provided transactional support.
University of Notre Dame
PhD in Biomedical Sciences: Microbiology and Immunology
Singha, U.K., Hamilton, V., and Chaudhuri, M., "Tim62, a Novel Mitochondrial Protein in Trypanosoma brucei, is Essential for Assembly and Stability of the TbTim17 Protein Complex", Journal of Biological Chemistry, August 2015.
Weems, E., Singha, U.K., Hamilton, V., Smith, J.T., Waegemann, K., Mokranjac, D., and Chaudhuri, M., "Functional Complementation Analyses Reveal that the Single PRAT-Family Protein of Trypanosoma brucei is a Divergent Homolog of Tim17 in Saccharomyces cerevisiae", Eukaryotic Cell, January 2015.
Hamilton, V., Singha, U.K., Weems, E., and Chaudhuri, M., "Trypanosome Alternative Oxidase Possesses Both an N-terminal and Internal Mitochondrial Targeting Signal", Eukaryotic Cell, February 2014.
Singha, U.K., Hamilton, V., Duncan, M., and Chaudhuri, M., "A Novel Protein Translocase of Mitochondrial Inner Membrane in Trypanosoma brucei", Journal of Biological Chemistry, March 2012.