Shubeena Chib, PhD

Technical Advisor, Silicon Valley



Shubeena Chib is a technical advisor in the Intellectual Property Practice Group. She has a strong background in biotechnology and life sciences. Shubeena's experience in drafting and prosecuting patents in a wide range of scientific and technical fields has helped her develop a keen understanding of how to protect valuable business assets. She has experience in building patent portfolios protecting pharmaceutical, life science, and medical device technologies; examples include: gene therapy, antibody therapeutics, CRISPR-Cas9 related technologies, ultrasound, and MRI technologies.

Previously, Shubeena worked as a technology transfer fellow at Oregon Health & Science University (OHSU), where she managed OHSU's intellectual property portfolio with specific focus on prior art search, patentability analysis, and patent drafting. This followed her OHSU neurobiology research associate work, where she led projects associated with identification and validation of biomarkers for Alzheimer's disease, and postdoctoral work focusing on virology.

Shubeena obtained her Ph.D. in Biochemistry from University of Arkansas for Medical Sciences with an emphasis in helicase enzyme kinetics. During Shubeena's years as a research associate, postdoctoral fellow, and graduate student, she published a number of peer-reviewed journal articles.

Bars and Courts
US Patent and Trademark Office
Biochemistry and Molecular Biology
University of Arkansas
Life Science
Devi Ahilya University
Botany/Plant Biology
University of Delhi



Ramanagoudr-Bhojappa, R., Chib, Shubeena, Byrd, Alicia K., Aarattuthodiyil, Suja, Pandey, M., Patel, Smita S., and Raney, Kevin D. (2013) "Yeast Pif1 helicase exhibits a one-base-pair stepping mechanism for unwinding duplex DNA". J. Biol. Chem. 288, 16185-95.

Gao, J., Zybailov, Boris L., Byrd, Alicia K., Griffin, Wezley C., Chib, Shubeena, Mackintosh, Samuel G., Tackett, Alan J., and Raney, Kevin D. (2015) "Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA". Chem. Commun., 51, 7242-7244.

Chib, Shubeena, Byrd, Alicia K., and Raney, Kevin D. (2016) "Yeast helicase Pif1 unwinds RNA:DNA hybrids with higher processivity than DNA:DNA duplexes". J. Biol. Chem. 291, 5889-901.

Byrd, Alicia K., Zybaylov, Boris L., Maddukuri, L., Gao, J., Jaiswal, M., Chib, Shubeena, Griffin, Wezley C., Mackintosh, Samuel G., Mac Nicol, A., Baldini, G., Eoff, Robert L., and Raney, Kevin D. (2016) "Evidence that G-quadruplex DNA mediates intracellular signaling through stress granule assembly in response to oxidative stress". J. Biol. Chem. 291, 18041-57.

Lopez CR, Singh S, Hambarde S, Griffin WC, Gao J, Chib Shubeena, Yu Y, Ira G, Raney KD, and Kim N (2017) "Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA". Nucleic Acids Res. 45, 5850-5862.

Griffin WC, Gao J, Byrd AK, Chib Shubeena, and Raney KD (2017) "A Biochemical and Biophysical Model of G-quadruplex DNA Recognition by Positive Coactivator of Transcription 4". J. Biol. Chem. 292, 9567-9582.